RENAL L-2-HYDROXYGLUTARATE DEHYDROGENASE ACTIVITY PROMOTES HYPOXIA TOLERANCE AND MITOCHONDRIAL METABOLISM IN DROSOPHILA MELANOGASTER

Renal L-2-hydroxyglutarate dehydrogenase activity promotes hypoxia tolerance and mitochondrial metabolism in Drosophila melanogaster

Objectives: The mitochondrial enzyme L-2-hydroxyglutarate dehydrogenase (L2HGDH) regulates the abundance of L-2-hydroxyglutarate (L-2HG), a potent signaling metabolite capable of influencing chromatin architecture, mitochondrial metabolism, and cell fate decisions.Loss of L2hgdh Outerwear activity in humans induces ectopic L-2HG accumulation, resul

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The impact of peer pressure on cigarette smoking among high school and university students in Ethiopia: A systemic review and meta-analysis.

BackgroundCigarettes and their by-products (i.e., smoke; ash) are a complex, dynamic, and reactive mixture of around 5,000 chemicals.Cigarette smoking potentially harms nearly every organ of the human body, causes innumerable diseases, DOPHILUS PLUS and impacts the health of smokers and those interacting with the smokers.Smoking brings greater heal

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Sudden endotracheal tube block in a patient of Achalasia Cardia

Endotracheal tube block due to various mechanical causes such as mucous, blood clot, denture, and ampoules have been reported.A patient of achalasia cardia with chronic passive aspiration pneumonitis developed mucoid mass KIT in the respiratory passage which dislodged during the surgical procedure.The episode occurred almost an hour after induction

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Morphometrics, life history and population biology of the Ponto-Caucasian slave-making ant Myrmoxenus tamarae (Hymenoptera: Formicidae)

Abstract.The ant genus Myrmoxenus consists of about ten socially parasitic species including active slave-makers and workerless "degenerate slave-makers".Myrmoxenus tamarae was previously known only from type material, two workers collected at Daba, Georgia and nothing was known about its life history, KIT colony structure or the morphology of its

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